The Hundred Stay Tokyo Shinjuku is located in the heart of the popular Shinjuku area. It is a 15 minute walk to Shinjuku Station. It is 1 km to the Toyama Park and 2 km from the Toyko Metropolitan Government buildings. The nearest transit point for the Hundred Stay Tokyo Shinjuku is the JR Okubo Station, a 3 minute walk.

The 175 rooms at the Hundred Stay Tokyo Shinjuku operate as fully furnished service apartments. The service apartments include high speed Internet access, LCD TV screens, Bose home theater systems, and designer furnishings. West Tower units have en suite washers and dryers. The layouts are varied, with apartments suitable for singles or families on offer.

The Hundred Stay Tokyo Shinjuku is a 21 level modern hotel with a contemporary décor. Amenities are divided between the two towers, East and West. The hotel offers a fully supported business center, multifunction space, and fitness rooms exclusively for guests. The lower levels have some mixed use retail space. Parking is available.